Preparations used to promote neural stem cell proliferation, preparations used to prevent or treat diseases associated with neural stem cell depletion, preparations used to promote posterior synaptic formation, prevention or prevention of diseases associated with reduced posterior synaptic formation Formulations used for treatment and screening methods

摘要

A preparation used for promoting proliferation of neural stem cells, containing a predetermined DNA encoding PQBP-1 or a polypeptide encoded by this DNA as an active ingredient, and used for the prevention or treatment of diseases associated with the decrease in neural stem cells Provided, a preparation used for promoting post-synaptic formation, a preparation used for preventing or treating a disease associated with a decrease in post-synaptic formation, and a screening method. The preparation used for promoting the proliferation of neural stem cells contains, as an active ingredient, DNA having the base sequence described in SEQ ID NO: 1 encoding PQBP-1, or a polypeptide encoded by these DNAs. Moreover, the formulation used for promotion of post-synaptic formation contains DNA having a base sequence described in SEQ ID NO: 1 encoding PQBP-1 or a polypeptide encoded by these DNAs as an active ingredient.