DACH1 BUILDS ARTERY NETWORKS THAT PROTECT AGAINST CARDIAC INJURY IN ADULTS

摘要

Methods and compositions are provided for expanding coronary artery networks in an adult mammal in vivo, by increasing activity or expression of the transcription factor DACH1 in capillary endothelial cells. Compositions and kits for practicing the methods and/or for use with the systems of the disclosure are also provided.