METHODS FOR REDUCING THC CONTENT IN COMPLEX CANNABINOID MIXTURES IN WHICH THC IS A MINOR COMPONENT

摘要

Disclosed herein is a method for upgrading a cannabinoid mixture that comprises tetrahydrocannabinol (THC) and one or more non-THC cannabinoids, when the cannabinoid mixture has a THC content of less than about 20 wt. %. The method comprises contacting the cannabinoid mixture with a benzoquinone reagent under reaction conditions comprising: (i) a reaction temperature that is within a target reaction-temperature range for the benzoquinone reagent and the cannabinoid mixture; and (ii) a reaction time that is within a target reaction-time range for the benzoquinone reagent, the cannabinoid mixture, and the reaction temperature; such that the THC content of the cannabinoid mixture is reduced to a greater extent than that of at least one of the one or more non-THC cannabinoids on a relative wt. % reduction basis.