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Compounds (I) Cl atoms are in 2,4,5- or 2,3,6-position; R=H or Me when 2,3,6-trichloro-compound; R=H when 2,4,5-trichloro compound; n=0 or 1; HX=anion.
Compounds (I) Cl atoms are in 2,4,5- or 2,3,6-position; R=H or Me when 2,3,6-trichloro-compound; R=H when 2,4,5-trichloro compound; n=0 or 1; HX=anion.
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机译:化合物(I)的Cl原子位于2,4,5-或2,3,6-位;当2,3,6-三氯化合物时,R = H或Me;当2,4,5-三氯化合物时,R = H; n = 0或1; HX =阴离子。
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Compounds (I) Cl atoms are in 2,4,5- or 2,3,6-position; R=H or Me when 2,3,6-trichloro-compound; R=H when 2,4,5-trichloro compound; n=0 or 1; HX=anion. The 2,4,5-trichloro compound is an analgesic with practically no side effect e.g. diuretic activity. The 2,3,6-trichloro compounds are tranquillisers, diuretics, and analgesics. The 2,4,5-trichloro compound has an oral ED50 in mice of 1.8 mg/kg. The 2,3,6-trichloro compound (R=H) has an ED50 in mice p.o of 44.8 mu g/kg. 2-2,3,6-trichlorobenzyl)-2-imidazoline.
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