METHOD FOR PREPARING THE SUBSTITUTED ISOTHYOL1 UCHEVIN1 The invention relates to the method of obtaining the derivatives of amides, in particular the substituted isothiourea, which has pharmacological activity. The proposed method for producing a substituted isothiourea of the general formula .- ^^ - (^ E,}, t ^ '(^^^^' 'X_LASR ^ where X is hydrogen, lower alkyl, amino or lower alkylthio; b ^ 1; n - 2-5; R— hydrogen, Ci — 4-, alkyl, aryl, or aralkyl; R * is saturated or unsaturated Ci — Cb-alkyl or (CH2) mZ, where m is 1-3; Z is substituted or unsubstituted aryl, hydroxyl, carboxyl, alkyl ^ mino or cyano group; R and R ^ together can form a 5-membered ring; 2A together with the adjacent carbon and nitrogen atoms is an unsaturated 5-6 membered heterocyclic ring, based on the well-known alkylation reaction of group 5 - C = S and consists in the fact that the thiourea of the general formula /? NK. 'South': '™' ^^ Agde A, X, B, n and R have the above meanings, are treated with a compound o