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Analogous Process for the preparation of 1,3,16,17-tetraoxygenerede 8alfa-ostratriener

机译:制备1,3,16,17-四氧合稀土8α-雌三酸酯的类似方法

摘要

1,3-Dihydroxy-8 alpha -estratrienes of the formula WHEREIN R is lower-alkyl and -A-B is WHEREIN R' is a saturated or unsaturated hydrocarbon group and R'' is lower-alkyl, aralkyl or phenyl, and the esters and ethers thereof, possess strong vaginotropic but only weak utertropic activity and are useful in the treatment of estrogenic deficiency conditions where uteral effects are not desired.
机译:式中,R 1是低级烷基,-AB是W时,R'是饱和或不饱和烃基,R”是低级烷基,芳烷基或苯基,式中的1,3-二羟基-8α-雌烯基酯它们的醚具有强的促阴道活性,但仅具有弱的子宫活性,可用于治疗不需要子宫作用的雌激素缺乏症。

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