6*111DIHYDROO111 OXODIBENZ *B*E* OXEBINEALKANOIC ACID AND ESTER THEREOF

摘要

6,11-Dihydro-11-oxodibenz[b,e]oxepinealkanoic acids of the formula I, their C1- to C4-alkyl esters and the pharmacologically compatible salts are prepared. An alpha -bromo-2-toluylic ester which is optionally substituted by halogen, C1- to C4-alkoxy, C1- to C4-alkyl or trifluoromethyl is reacted with an alkyl ester of a hydroxyphenylacetic acid. The resulting diester is hydrolysed, cyclised and, where appropriate, converted into the corresponding alkyl ester. The resulting compounds can be used as anti-inflammatory and analgesic agents. IMAGE