1,4-DISUBSTITUTED 4-IMIDAZOLIN-2-ONES,1,4-DISUBSTITUTED IMIDAZOLIN-2-ONES AND 1,4-DISUBSTITUTED IMIDAZOLIDIN-2-THIONES AND THEIR USE IN NON-ASYMMETRIC SYNTHESIS OF TETRAMISOLE LEVAMISOLE AND THEIR DERIVATIVES

摘要

Procedure for preparing substituted imidazolidine derivatives of formula HY wherein R2 is phenyl or phenyl substituted with up to two groups consisting of C1-C6 alkyl, halo or trifluoromethyl; and Y is a pharmaceutically acceptable anion, characterized by heating a substituted imidazolidinethione of the formula: *** See image 01 *** See image 02 (Machine-translation by Google Translate, not legally binding)