New composed 2 - amino - aa - dicyanoacetophenone and amino 2 - 3 - cyano - 4 hydroxyquinoline, their preparation and their application for the preparation of 2 - 4 - hydroxyquinolines amino -

摘要

P the invention relates to the preparation of 2 - amino - 4 - hydroxyquinolines. / p & & p & the method consists in reacting with the anhydrides malononitrile in an inert solvent in the presence of a base in order to produce the 2 - amino - 3 - cyano - 4 - hydroxyquinolines and of the 2 - amino - α, α - dicyanoacétophénones which are then hydrolyzed and decarboxylated in the acid or basic conditions for producing the 2 - 4 - hydroxyquinolines amino -. The 2 - amino - 4 - hydroxyquinolines obtained by the process of the invention are intermediates for the preparation of acids, 1 - oxo - 1h - 6 - alkoxypyrimidoøl, 2 - alquinoleine - 2 - carboxylic acids and their esters, which are endowed with properties - allergic. / p