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Quat. procaine halide(s) - used as local anaesthetics, muscle relaxants and bactericides, are prepd. from procaine and excess alkyl halide
Quat. procaine halide(s) - used as local anaesthetics, muscle relaxants and bactericides, are prepd. from procaine and excess alkyl halide
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机译:夸制备普鲁卡因卤化物-用作局部麻醉剂,肌肉松弛剂和杀菌剂。来自普鲁卡因和过量的烷基卤
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摘要
Procaine derivs. of formula (I) are new: In (I) R is ethyl, propyl, butyl, pentyl or -CH2CH2-(sic) and X is halogen, esp. Br. (I) have greater activity as local anaesthetic than procaine base, and the cpds. also have muscle relaxing and bactericidal activity. (I) are prepd. by treating procaine base with 400-1000% excess of the desired normal alkyl halide and refluxing the mixt. until quaternisation is complete.
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