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DIAGNOSTIC AGENT LABELLED WITH TECHNETIUMM99M WHICH MOVES IN CYSTIC OR HEPATIC DUCT

机译:在囊性或肝性导管中移动的TechniciumM99M标记的诊断剂

摘要

PURPOSE:To obtain a diagnostic agent which is hard to be discharged into urine, by bringing an aqueous solution of a 99mTc compound into contact with a carrier obtained by dissolving salicylaldehyde, a prescribed alpha-amino acid and a stannite in water. CONSTITUTION:Salicylaldehyde or a derivative such as 5-chlorosalicylaldehyde, which does not have a hydrophilic functional group except for a formyl group and a hydroxyl group which are the constituents of the salicylaldehyde, an alpha-amino acid such as phenylalanine, which does not have a hydrophilic side chain except for a carboxyl group and an amino group which are the constituents of the amino acid, and a stannite such as stannous chloride are dissolved in water so that a non-radioactive carrier is obtained. A physiological soline solution containing a pertechnetate of 99mTc such as sodium pertechnetate is mixed with the non-radio-active carrier. The mixture is left at room temperature, thereby producing a diagnosing agent.
机译:目的:通过使99mTc化合物的水溶液与通过将水杨醛,规定的α-氨基酸和亚锡酸盐溶解在水中而获得的载体接触,来获得难以排入尿液的诊断剂。组成:水杨醛或诸如5-氯水杨醛之类的衍生物,它除了具有作为水杨醛成分的甲酰基和羟基外不具有亲水性官能团,而α-氨基酸如苯丙氨酸则不具有将除构成氨基酸的羧基和氨基以外的亲水性侧链和诸如氯化亚锡的亚锡盐溶解在水中,从而获得非放射性载体。将包含99m Tc高tech酸酯的生理性索恩溶液(例如高tech酸钠)与非放射性载体混合。将混合物在室温下放置,从而产生诊断剂。

著录项

  • 公开/公告号JPS5596456A

    专利类型

  • 公开/公告日1980-07-22

    原文格式PDF

  • 申请/专利权人 NIHON MEDIPHYSICS CO LTD;

    申请/专利号JP19790005096

  • 发明设计人 KATOU MAKOTO;HATSUE MASAAKI;

    申请日1979-01-18

  • 分类号G01N33/60;G01N33/50;

  • 国家 JP

  • 入库时间 2022-08-22 18:46:49

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