Process for the preparation of New acid derivatives (8rs, 12rs 9RS, (5Z, 15rs), 13e) 9.15 - dihydroxy - 16 - 18,19,20 TRINOR (or 17,18,19,20 Prosta - tetranor) 513 - dienoico and intermediaries for exclusive use in this procedure

摘要

Novel 11-desoxy-prostaglandin F2 derivatives of the formula IMAGE I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, an alkali metal, an equivalent of an alkaline earth metal, magnesium or organic amine base, R1 and R2 are individually seleced from the group consisting of hydrogen and methyl and X is selected from the group consisting of IMAGE and a 5 to 6 membered heterocycle optionally substituted with at least one member of the group consisting of halogen, -CN and alkyl of 1 to 5 carbon atoms and X1 is a 6 member heterocycle with the wavy lines indicating that the hydroxy may be in either one of the two possible alpha and beta positions having hypotensive activity and process for their preparation.