MODIFIED GLUCOSAMINOGLYCANS HAVING ANTILIPEMIC ACTIVITY AND ESSENTIALLY DEVOID OF ANTICOAGULANT ACTIVITY

摘要

Copolymers of formula I are described IMAGE (I) in which A is the monomeric unit of a natural or synthetic polymer, m is the degree of polymerization; m and n are different one from the other, and m is a number between about 300 and about 10,000 and n is a number between about 100 and about 250; R is a quaternary ammonium radical; X- is an anion. A may be the monomeric unit of starch or the monomeric unit of hydroxyethylcellulose. The substances exhibit substantial activity in the treatment of infections of the skin and mucosa and fungus infections and in general, high bactericidal activity accompanied by low toxicity.