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A New procedure for the preparation and aroilamino amino - N - fenilpiridinaminas

机译:一种新的制备和制备氨基氨基-N-芬尼吡啶胺的新方法。

摘要

Process for the preparation of amino and aroilamino - N - fenilpiridinaminas, of General formula (i), in which q is selected from Hydrogen or Halogen; R1 and R2 are lower alcohilo or taken together form the nitrogen Atom with the adjacentA Heterocyclic Amine or other means; R3 aroilamino; ar is phenyl or substituted phenyl; alc1 is a straight chain or branched Hydrocarbon; Z is Hydrogen, halogen or lower alcohilo and means; and Hydrogen or lower alkoxy, their acid Addition Salts and pharmaceutically aceptab Les.Consists in subjecting a reduction reaction of a compound of formula (ii), to convert the Nitro Group to an amino Group and a compound of formula (iii), and reacting The Compound of formula (iii) with a aroilo Halide to obtain an aroilamino - N - N - fenilpiri Dinamina.de antidepressant Agent Application.
机译:通式(i)的氨基和芳胺基氨基-N-苯并吡喃氨基丁酸酯的制备方法,其中q选自氢或卤素; R1和R2是低级醇基或与相邻的杂环胺或其它方式一起形成氮原子。 R3 aroilamino; ar是苯基或取代的苯基; alc1是直链或支链烃; Z是氢,卤素或低级醇基,是指;氢或低级烷氧基,它们的酸加成盐和药学上可接受的化合物,包括使式(ii)的化合物还原反应,将硝基基团转化为氨基和式(iii)的化合物,并进行反应。式(iii)的化合物与卤代芳烃一起获得芳油基氨基-N-N-非尼替尼二抗抗抑郁剂的应用。

著录项

  • 公开/公告号ES8507496A1

    专利类型

  • 公开/公告日1985-12-16

    原文格式PDF

  • 申请/专利权人 A. H. ROBINS COMPANY INCORPORATED;

    申请/专利号ES19840531221

  • 发明设计人

    申请日1984-04-02

  • 分类号C07D213/74;C07D471/04;

  • 国家 ES

  • 入库时间 2022-08-22 07:37:44

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