首页> 外国专利> A procedure for preparing a Peptide that has an influence on the function of the pituitary gland

A procedure for preparing a Peptide that has an influence on the function of the pituitary gland

机译:一种影响垂体功能的肽的制备方法

摘要

Process for preparing peptides that have influence on the function of the pituitary gland.Comprising: (a) make Short peptides or amino acids together to form an intermediate Compound of formula (ii), which is a protecting Group; (b) Splitting the Protecting groups or the link of Anchoring Peptide of formula (ii), treating the compound with HF, 0jc, to obtain the peptid Or of formula (i); and (c) convert the Peptide, resulting in an addition of non-toxic Salt thereof.Being: r40k Wing, or desr40 carboxyl portion; and The residue of the c-terminal amino acid; x1 to X7, x8 H or Protective Group and protective Group, the Resin Anchor bracket or des X8, in whose Case The residue in the c-terminal carboxyl and has a portion that is used for promo. See the release of growth hormone by the pituitary gland in Mammals.
机译:制备影响垂体功能的肽的方法。包括:(a)使短肽或氨基酸一起形成式(ii)的中间体化合物,其为保护基; (b)拆分式(ii)的保护基团或锚定肽的连接,用HF,0jc处理该化合物,以获得式(i)的肽Or;存在:r40k Wing或desr40羧基部分;和(c)转化该肽,得到其无毒盐。 c-末端氨基酸残基; x1至X7,x8 H或保护基和保护基,树脂锚定支架或des X8,在这种情况下,c末端羧基上的残基具有一部分用于促销。观察哺乳动物垂体中垂体释放的生长激素。

著录项

  • 公开/公告号ES8606399A1

    专利类型

  • 公开/公告日1986-10-01

    原文格式PDF

  • 申请/专利权人 THE SALK INSTITUTE FOR BIOLOGICAL STUDIES;

    申请/专利号ES19830526201

  • 发明设计人

    申请日1983-10-03

  • 分类号C07K7/10;A61K37/02;

  • 国家 ES

  • 入库时间 2022-08-22 07:37:29

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号