首页>
外国专利>
monoklonala antikroppar och antigen foster human ej - smaocellrelaterad lungkancer och andra humana vissa kancerformer.
monoklonala antikroppar och antigen foster human ej - smaocellrelaterad lungkancer och andra humana vissa kancerformer.
展开▼
机译:单克隆抗体和抗原性胎儿是人类非小细胞肺癌和其他人类某些癌症。
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention is concerned with novel monoclonal antibodies which bind strongly to a protein antigen associated with human non-small cell lung carcinomas ("NSCLC") human small cell lung carcinomas and certain other human carcinomas including many carcinomas of the colon and breast. The antibodies bind to normal human cells to a much lesser degree than to tumor cells. The antibodies find use both in diagnostic methods such as the detection of malignant cells associated with NSCLC and in therapeutic methods for treatment of human in NSCLC and certain other human carcinomas. Also disclosed is a novel 110,000 dalton glycoprotein antigen found on the cell surface of human non-small lung carcinoma tumor cells and on cells from certain other human cancers. The amino terminal amino acid sequence of this antigen is: IMAGE +TR IMAGE in which X represents an unidentified amino acid.
展开▼