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Process for preparing a 2-alkyl- or 2-phenyl-1,4,5,6-tetrahydropyrimidineand and process for the preparation of 2-alkyl- or 2-phenyl- pyrimidines

机译:制备2-烷基-或2-苯基-1,4,5,6-四氢嘧啶的方法和制备2-烷基-或2-苯基嘧啶的方法

摘要

The invention relates to a process for preparing a 2-alkyl-1,4,5,6-tetrahydropyrimidine with the formula where R represents a straight or branched chain with 1-8 C-atoms or a phenyl group from 1,3-diaminopropane and an alkanecarboxylic acid, in which the alkyl group of such an acid is the same as the R group described above, in which process the starting materials are reacted in the gas phase in the presence of an oxide catalyst at a temperature of between 250 and 450◊C and from the reaction mixture thus obtained the 2-alkyl-1,4,5,6-tetrahydropyrimidine is recovered.
机译:本发明涉及一种制备具有下式的2-烷基-1,4,5,6-四氢嘧啶的方法 <图像文件=“ IMGA0001.GIF” he =“ 36” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 29” /> 其中R代表具有1-8个碳原子或1,3-二氨基丙烷和链烷羧酸的苯基的直链或支链,其中该酸的烷基与上述R基团相同,其中在250-450℃之间的温度下,在氧化物催化剂存在下,使原料在气相中反应,并从反应混合物中回收2-烷基-1,4,5,6-四氢嘧啶。

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