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Specific antibodies body against heart muscle myosin - light chains, their preparation and use in a reagent for the determination of heart muscle myosin - light chains
Specific antibodies body against heart muscle myosin - light chains, their preparation and use in a reagent for the determination of heart muscle myosin - light chains
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机译:抗心肌肌球蛋白轻链的特异性抗体,其制备方法和用于测定心肌肌球蛋白轻链的试剂
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摘要
The present invention provides a specific antibody against heart muscle light chains (HMLC) with a cross-reactivity against skeletal muscle light chains (SMLC) of less than 5%. The present invention also provides a process for the preparation of this specific antibody, wherein a mammal is immunized with HMLC I and/or HMLC II and the crude serum is recovered and subjected to an immunosorptive purification on an SMLC immune adsorbent based on silicate. Furthermore, the present invention provides a reagent for the determination of HMLC which contains antibodies against HMLC according to the present invention.
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