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METHOD FOR PRODUCING ANIMAL SERUM WITH REDUCED PROTEASE AND INHIBITOR ACTIVITY, ANIMAL SERUM, AND USE OF THIS SERUM AS AN ADDITION TO CULTURAL MEDIA
METHOD FOR PRODUCING ANIMAL SERUM WITH REDUCED PROTEASE AND INHIBITOR ACTIVITY, ANIMAL SERUM, AND USE OF THIS SERUM AS AN ADDITION TO CULTURAL MEDIA
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机译:具有降低的蛋白酶和抑制剂活性的动物血清的生产方法,动物血清以及将该血清用作文化培养基的补充
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摘要
The addition of animal sera to cell cultures has adverse effects on the activity of the cell proteins to be isolated. The invention thus relates to a process for the treatment of an animal serum in which the serum is treated with at least one nucleophilic agent. The invention also relates to a serum treated by the claimed process and to the use of this serum as additive to a culture medium for cell cultures. The negative proteolytic and inhibitory properties of the sera are selectively reduced so that the activity of the proteins to be isolated is retained to a high degree when the sera according to the invention are used.
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