ANALOGIFREMGANGSMAADE FOR THE PRODUCTION OF 7-OE2- (2-imino-4-thiazoline-4-YL) -2-HYDROXY-IMINOACETAMIDOAA-3- (substituted methyl) -3-cephem-4-carboxylic acid (syn) -isomers or pharmaceutically ACCEPTABLE SALTS OR ESTERS THEREOF, AND syn -isomer of 2- (4-thiazoline-4-yl) acetic acid derivatives

摘要

Disclosed are 2-(syn)-hydroxyimino-acetamide derivatives of the formula: IMAGE wherein Y is hydrogen, hydroxyl, an acyloxy, carbamoyloxy, a quaternary ammonium or a nitrogen-containing heterocyclic ring-substituted thio group; or pharmaceutically acceptable salts or esters thereof are useful as antibacterial agents. Also disclosed are processes for producing them.