DISINTEGRATABLE TABLET CONTAINING GEMFIBROZIL IN TWO GRANULATION FORMS TO PROVIDE BOTH IMMEDIATE AND ENTERIC RELEASE

摘要

A disintegratable gemfibrozil tablet providing both immediate and enteric release is compressed from a mixture of a first granulation of gemfibrozil with at least one acid-disintegratable binder and a second granulation formed from the first granulation but regranulated or coated with an alkali-disintegratable formulation of at least one substantially alkali-soluble and substantially acid-insoluble polymer.