use of isothiosemicarbazonen to combat infectious viruses

摘要

An antiviral drug contains as its effective component an isothiosemicarbazone represented by the following general formula (I) or an acidic salt thereof: IMAGE (I) wherein R1 represents a halogen atom, a lower (C1-C6) alkyl group, a hydroxy group, a phenyl group which may be or may not be substituted with an alkoxy group containing 1 to 12 carbon atoms, or an unsubstituted or substituted phenylethynyl group represented by the following general formula (II): IMAGE (II) (wherein R5 and R6 may be the same or different, and they each represent a hydrogen atom, a halogen atom, a lower (C1-C6) alkyl group, a hydroxy group or an alkoxy group containing 1 to 12 carbon atoms); R2 represents a hydrogen atom or a lower (C1-C6) alkyl group; R3 represents a lower (C1-C6) alkyl group or a benzyl group; R4 represents a hydrogen atom or a lower (C1-C6) alkyl group. Many of these effective component compounds not only have antiviral activity (especially against influenza virus), but also prevent the breeding of and exterminate plant pathogenic molds.