Process for the production of a aerobico microorganism in a culture fed batch culture or culture still continues, with recycling of cells.Apparatus for controlling the concentration of the carbon source substrate and process for producing L-lysine by fermentation

摘要

A low concentration of the carbon source of the substrate in the culture vessel is maintained during the feeding of the culture in aerobic cultures which are of the batch type, continuous type or continuous type with recycling of the cells, by controlling the increase in the pH or the dissolved oxygen content in the culture medium and by intermittently adding the feed solution to the culture vessel at a flow rate calculated using a computer-controlled feed regulation device. Application: production of L-lysine by fermentation with an enhanced productivity, higher concentrations of the accumulated product and increased L-lysine yields. IMAGE