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Liquid composition for use in women's intimate hygiene and method of inibicao of production of toxin - 1 of toxic shock syndrome

机译:女性私密卫生用液体组合物和中毒性休克综合症毒素-1的产生途径

摘要

Nonabsorbent products and douche compositions for cleansing and placement within the vagina contain an amount of a compound effective to inhibit the production of toxic shock syndrome toxin-1 and Enterotoxins A, B and C when the products are brought into contact with the bacteria. The products and compositions of this invention are also effective in combatting streptococcal pyrogenic exotoxin and hemolysin production by Groups A, B, F and G streptococci. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C8-C18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C8-C18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.
机译:用于清洁和放置在阴道内的非吸收性产品和冲洗组合物包含一定量的化合物,当该化合物与细菌接触时,该化合物可有效抑制中毒性休克综合症毒素1和肠毒素A,B和C的产生。本发明的产品和组合物还可有效抵抗A,B,F和G族链球菌产生的链球菌热原性外毒素和溶血素。该化合物选自多元脂族醇和C8-C18脂肪酸的单酯;多元脂族醇和C8-C18脂肪酸的二酯;及其混合物。单酯和二酯具有至少一个与其脂族醇残基缔合的羟基。

著录项

  • 公开/公告号BR9104710A

    专利类型

  • 公开/公告日1992-06-16

    原文格式PDF

  • 申请/专利权人 JOHNSON & JOHNSON;

    申请/专利号BR19919104710

  • 发明设计人 SUSAN K. BROWN-SKROBOT;MARY M. IRVING;

    申请日1991-10-30

  • 分类号A61K31/23;

  • 国家 BR

  • 入库时间 2022-08-22 05:36:30

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