GONADOLIBEINDERIVATER, FARMACEUTISK ACCEPTABLE SYREADDITIONSSALTE OG COMPLEXER HERAF SAMT EN FREMGANGSMAADE TIL FREMSTILLING AF DISSE OG ET FARMACEUTISK PRAEPARAT INDEHOLDENDE DISSE

摘要

The invention relates to novel gonadoliberine derivatives of the general formula (I) IMAGE (I) wherein X represents an -O-R group wherein R is a benzyl group or a C1-4 alkyl group, an IMAGE group wherein R1 and R2 independently stand for hydrogen, a C1-5 alkyl, aryl, aryl-C1-2-alkyl, morpholino, 1-indolinyl or 1-pyrrolidinyl group, Y is a glycine amide or a C1-4-alkyl-amide group, the addition salts thereof formed with acids used in therapy and complexes thereof as well as pharmaceutical compositions containing them, furthermore to a process for the preparation of the above compounds. The reproductive processes of vertebrates can be advantageously influenced with the compounds of general formula (I).