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Novel derivatives of 6-methyl 19-NOR progesterone¹substituted in postion 3 and a process for their production

机译:在3位取代的6-甲基19-NOT孕酮的新型衍生物及其制备方法

摘要

The invention relates to the field of organic chemistry and more particularly to therapeutical chemistry. It relates in particular to 6-methyl 19-nor pregna 4,6-diene 20-one having general formula (I) wherein R1? is hydrogen and R2? is a radical OR3? wherein R3? is hydrogen or an acyl residue or R1? and R2? form together a group oximino =N-OR4?, or alkylene dioxy optionally substituted, or R1? and R2? are each a lower alkoxy radical or alkylene dioxy optionally substituted and Ac is the acyl residue of an organic carboxylic acid. The compounds of formula (I) are active principles of progesteronic medicaments.
机译:本发明涉及有机化学领域,尤其涉及治疗化学。特别是涉及具有通式(Ⅰ)的6-甲基19-去甲炔丙基4,6-二烯20-,其中R 1是-。是氢和R2?是激进的OR3?其中R3?是氢或酰基残基或R1?和R2?一起形成一个基团:肟基= N-OR4′,或任选取代的亚烷基二氧基,或R1′。和R2?各自为任选被取代的低级烷氧基或亚烷基二氧基,并且Ac为有机羧酸的酰基残基。式(I)的化合物是孕激素药物的活性成分。

著录项

  • 公开/公告号IE912539A1

    专利类型

  • 公开/公告日1992-01-29

    原文格式PDF

  • 申请/专利权人 LABORATOIRE THERAMEX SA;

    申请/专利号IE19910002539

  • 发明设计人

    申请日1991-07-19

  • 分类号C07J7/00;C07J21/00;C07J41/00;

  • 国家 IE

  • 入库时间 2022-08-22 05:35:19

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