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COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA

机译:前列腺肥大和/或治疗前列腺增生症的联合疗法

摘要

The invention relates to a combination therapy for the prophylaxis and / or treatment of benign prostatic hyperplasia in warm-blooded animals susceptible to developing such disease. This therapy comprises administering a combination of at least two compounds selected from the group consisting of an activity inhibitor of 5alpha-reductase, with an anti-estrogen, for an activity aromatase inhibitor, with an inhibitor of dehydrogenase activity 17beta-hydroxysteroid and in some cases, an antiandrogen and / or an LHRH agonist. Pharmaceutical compositions used in such treatment and pharmaceutical kits containing such compositions are disclosed.
机译:本发明涉及在易患这种疾病的温血动物中预防和/或治疗良性前列腺增生的联合疗法。该疗法包括给予选自以下的至少两种化合物的组合:5α-还原酶活性抑制剂和抗雌激素,用于活性芳香酶抑制剂,以及脱氢酶活性抑制剂17β-羟基类固醇,在某些情况下,抗雄激素和/或LHRH激动剂。公开了用于这种治疗的药物组合物和包含这种组合物的药盒。

著录项

  • 公开/公告号EP0480950A1

    专利类型

  • 公开/公告日1992-04-22

    原文格式PDF

  • 申请/专利权人 ENDORECHERCHE INC.;

    申请/专利号EP19900909598

  • 发明设计人 LABRIE FERNAND;

    申请日1990-07-05

  • 分类号A61K31/135;A61K31/16;A61K31/165;A61K31/565;A61K31/566;A61K31/568;A61K31/57;A61K31/575;A61K31/585;A61K45/06;A61P13/08;A61P35/00;A61P43/00;C07J1/00;C07J41/00;

  • 国家 EP

  • 入库时间 2022-08-22 05:29:27

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