首页>
外国专利>
NEW SUBSTANCE HAVING ANTIHYPERTENSIVE ACTION, ANTIHYPERTENSIVE AGENT, HEALTHY FOOD AND ITS PRODUCTION
NEW SUBSTANCE HAVING ANTIHYPERTENSIVE ACTION, ANTIHYPERTENSIVE AGENT, HEALTHY FOOD AND ITS PRODUCTION
展开▼
机译:具有抗高血压作用,抗高血压药物,健康食品及其生产的新物质
展开▼
页面导航
摘要
著录项
相似文献
摘要
PURPOSE: To obtain the subject new substance useful as an antihypertensive agent, etc., having low side effects, by fractionating an extract of threshed buckwheat seed with an aqueous solvent by gel filtration column chromatography and collecting a fraction having strong ACE inhibitory activity. ;CONSTITUTION: An extract of threshed buckwheat seed and/or buckwheat flour with an aqueous solvent such as water and/or alcohol, solution of salt, etc., is fractioned by gel filtration column chromatography and collected a fraction having strong inhibitory activity against angiotensin-I converting enzyme. The prepared fraction with ACE inhibitory activity is fractioned by adsorption column chromatography such as silica gel, and a fraction having strong ACE inhibitory activity is collected, the fraction having strong ACE inhibitory activity is again subjected to column chromatography by gel filtration and a purified fraction having concentrated strong ACE inhibitory activity is collected to give the objective new substance comprising a compound (salt) of the formula having ACE inhibitory activity.;COPYRIGHT: (C)1993,JPO&Japio
展开▼