Composition which FOERSTAERKER DEN MAGNETISKA RESONANSBILDEN OCH SOM comprises an KELATKOMPLEX, SOM BESTAOR AV EN KELATERANDE FOERENING OCH EN PARAMAGNETISK JON OCH KALCIUMSALT SAMT ANVAENDNING AV KELATKOMPLEXET OCH KALCIUMSALTET VID FRAMSTAELLNING AV Denna Kompositio Foer ATT ..........

摘要

In a method of imaging body tissue in a patient, comprising administering to the patient an effective amount of a pharmaceutical agent for affecting the relaxation times of atoms in body tissues undergoing NMR diagnosis, whereby image contrast is enhanced, said agent comprising an amount, effective to affect such relaxation times, of a paramagnetic, physiologically compatible salt of a physiologically compatible chelate complex of an ion of a lanthanide element of atomic numbers 57-70, or of a transition metal of atomic numbers 21-29, 42, or 44; and a pharmaceutically acceptable carrier, and subjecting the patient to NMR tomography, the improvement wherein said salt of said chelate complex is the calcium or magnesium salt. Such salts are new as are some of the complexing chelates.