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KOMPLEKSDANNENDE MIDLER OG MAALSOEKING AV RADIOAKTIVE IMMUNOREAGENSER NYTTIGE INNEN TERAPEUTISKE OG DIAGNOSTISKE BILDEDANNENDE SAMMENSETNINGER OG FREMGANGSMETODER
KOMPLEKSDANNENDE MIDLER OG MAALSOEKING AV RADIOAKTIVE IMMUNOREAGENSER NYTTIGE INNEN TERAPEUTISKE OG DIAGNOSTISKE BILDEDANNENDE SAMMENSETNINGER OG FREMGANGSMETODER
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机译:用于治疗性和诊断性想象组成和程序的放射免疫剂的复合材料和靶向
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摘要
Tripyridyl macrocyclic compounds that are employed in the production of a complexing agent for use in targeting radioactive immunoreagents with the following formula are disclosed: IMAGE wherein R1 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, aryl, aryloxy, heterocyclyl or a protein reactive group; the two R2 groups, taken together, represent a bridging group serving to complete a macrocyclic ring, the bridging group containing at least one heteroatom and at least one alkylene group which form part of the resulting macrocyclic ring; R3 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, aryl, aryloxy, heterocyclyl, or a protein reactive group; R5 represents alkyl or alkoxy; and R6 represents a protein reactive group.
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