ACTIVE SUBSTANCE-CONTAINING PLASTER OF THE CONTROLLED ADMINISTRATION OF ACTIVE SUBSTANCES TO THE SKIN, THE USE THEREOF AND A PROCESS FOR THE CONTROLLED ADMINISTRATION OF ACTIVE SUBSTANCES TO THE SKIN

摘要

THE INVENTION RELATES TO AN ACTIVE SUBSTANCE-CONTAINING PLASTER FOR THE CONTROLLED ADMINISTRATION OF ACTIVE SUBSTANCES TO THE SKIN, WHICH HAS A BACK AND A SKIN SIDE, WITH A BACK LAYER , AN ACTIVE SUBSTANCE RESERVOIR DIVIDED SUBSTANTIALLY PERPENDICULARLY TO THE SKIN CONTACT SURFACE OF THE PLASTER AND HAVING ONE OR MORE ACTIVE SUBSTANCES, A CONTACT ADHESIVE ON THE SKIN SIDE AND OPTIONALLY A COVER LAYER DETACHABLE PRIOR TO THE APPLICATION OF THE PLASTER, IN WHICH IT IS POSSIBLE TO REDUCE THE ACTIVE SUBSTANCE RELEASE SURFACE OF THE PLASTER BY A PREDETERMINED AMOUNT THROUGH THE REMOVAL OF PART OF THE ACTIVE SUBSTANCE RESERVOIR, WHERE AT LEAST ONE ACTIVE SUBSTANCE RESERVOIR PART IS DETACHABLE FROM THE SKIN, WHILST LEAVING BEHIDN ONE OR MORE ACTIVE SUBSTANCE RESERVOIR PARTS, THE PART OF THE ACTIVE SUBSTANCE RESERVOIR REMAINING ON THE SKIN HAVING A BETTER ADHESION TO THE SKIN THAN TO THE BACK LAYERS AS WELL AS TO THE USE OF THE PLASTER FOR LOCAL AND SYSTEMIC TRANSDERMAL ACTIVE SUBSTANCE ADMINISTRATION IN HUMAN OR ANIMAL MEDICINE OR IN COSMETIC. (FIG. 1)