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Pharmaceutical composition with an HMG - COA reductase inhibitor base, for treatment of benign prostatic hypertrophy (enlarged prostate gland)

机译:具有HMG-COA还原酶抑制剂基的药物组合物,用于治疗前列腺肥大(前列腺肥大)

摘要

Herein described is the use of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors in the treatment of prostatic hypertrophy; it is a new therapeutic utilization of such class of current pharmaceuticals noted as effective cholesterol reducers. This invention requires pharmaceutical preparations, administered by parenteral, oral, transdermic methods, to effectively engage in the treatment of prostatic hypertrophy and characterized by the fact that they contain, as a new character, as a principle active agent, an HMG-CoA inhibitor The results include a sensible reduction in the volume of the gland and a marked morphological mutation in the tissue with consequent pathological improvement.
机译:本文描述了3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂在治疗前列腺肥大中的用途。这是被称为有效的胆固醇降低剂的这类当前药物的新治疗用途。本发明需要通过肠胃外,口服,透皮方法给药的药物制剂,以有效地参与前列腺肥大的治疗,其特征在于它们包含作为主要活性剂的HMG-CoA抑制剂作为新的特征。结果包括显着减少腺体的体积和组织中明显的形态学突变,从而改善病理状况。

著录项

  • 公开/公告号IT1238011B

    专利类型

  • 公开/公告日1993-06-21

    原文格式PDF

  • 申请/专利权人 PULITZER ITALIANA S.R.L.;

    申请/专利号IT19890048658

  • 发明设计人 BERTONE EVARISTO;

    申请日1989-12-13

  • 分类号5A61KA;

  • 国家 IT

  • 入库时间 2022-08-22 05:10:01

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