首页> 外国专利> Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases

Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases

机译:包含经8-甲氧基补骨脂素处理过的t淋巴细胞或从其分离的细胞膜的制剂,用于预防或治疗自身免疫性疾病

摘要

Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoactivatable psoralen cross-linking agent, such as 8-methoxypsoralen, and then photoactivated. The active principle may also be the membrane fraction of such cells. Such preparations may be formulated into pharmaceutical compositions and administered to prevent or treat autoimmune diseases.
机译:提供了用于预防或治疗自身免疫疾病的药物制剂,其中活性成分是针对待治疗的自身免疫疾病的活化的T淋巴细胞,该细胞已通过与可光活化的补骨脂素交联剂(例如8)一起孵育进行了处理-甲氧基补骨脂素,然后光活化。活性成分也可以是此类细胞的膜部分。可以将这样的制剂配制成药物组合物并给药以预防或治疗自身免疫疾病。

著录项

  • 公开/公告号IL85746A

    专利类型

  • 公开/公告日1994-05-30

    原文格式PDF

  • 申请/专利权人 YEDA RESEARCH AND DEVELOPMENT CO. LTD.;

    申请/专利号IL19880085746

  • 发明设计人

    申请日1988-03-15

  • 分类号A61K35/14;

  • 国家 IL

  • 入库时间 2022-08-22 04:45:37

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