PARTICLES OF CRYSTALLINE ANTI-CANCER AGENT HAVING A SURFACE MODIFIER ADSORBED ONTO THE SURFACE THEREOF IN AN AMOUNT SUFFICIENT TO MAINTAIN A PARTICLE SIZE LESS THAN 1000 NM

摘要

Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by intravenous injection.