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Second amine - anti- hypertension constituent and its application null of nitrogen oxide

机译:二胺-抗高血压药成分及其一氧化氮的应用价值

摘要

This invention concerns anti-hypertensive compositions and a method of lowering blood pressure in mammals. The active component of the compositions is a compound of the formula: IMAGE I wherein R1 and R2 are independently chosen from straight chain and branched chain C1-C12 alkyl groups and benzyl, with the proviso that no branch occur on the alpha carbon atom of the alkyl groups; or R1 and R2 together with the nitrogen atom they are bonded to form a pyrrolidino, piperidino, piperazino or morpholino group, M+is a pharmaceutically acceptable cation, wherein X is the valence of the cation.
机译:本发明涉及抗高血压组合物和降低哺乳动物血压的方法。该组合物的活性成分是下式的化合物:其中R 1和R 2独立地选自直链和支链C 1 -C 12烷基和苄基,条件是在α碳原子上不存在支链烷基; R 1和R 2与氮原子一起键合形成吡咯烷基,哌啶子基,哌嗪子基或吗啉代基团,M +为药学上可接受的阳离子,其中X为阳离子的化合价。

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