25,26,27 trinor 1, 2 epokishikoresuta 4,6 diene 3 on 24 Acid methyl ester

摘要

This invention provides a new method for preparing 26,26,26,27,27,27-hexafluoro-1,25-dihydroxycholesterol. The method permits the use of cholenic acid or an ester of cholenic acid as the starting material and the preparation of a compound which can be readily converted into a highly active derivative of vitamin D, 26,26,26,27,27,27-hexafluoro-1 alpha ,25-dihydroxycholecalciferol.