Derivative of amidinofenilalanina antithrombotic and amidinopiridilalanina

摘要

Refers to a compound of formula (i) where X is 1: Ch, N; 2) and is a alquileno c3-c5 monounsaturated can be replaced with a methylene or c1-c4 alkyl R1 is H, 3);A c1-c4 alkyl can be substituted with a c1-c4 alkoxyl, Oh, nr5r6, conr5r6 C3 C6 or cycloalkyl, aryl, or a alquenilo C3 C6; R2 is H, 4)A c1-c4 alkyl can be substituted with a c1-c4 alkoxyl, Oh, nr5r6, conr5r6 C3 C6 or cycloalkyl, aryl or conr5r6; 5); R3 and R4 are h,C1-c4 alkyl can be replaced with a nr5r6; c1-c4 alkoxyl, Halo, and conr5r6 aryl; 6) R5 and R6 are h, c1-c4 alkyl; 7) M and N vary from 1 to 3; it may be useful as Thrombin inhibitor