Method for the separation of isomers of a crown ether, allowing specially the recuperation of pure isomers cis-syn-cis of dicyclohexyl 18-crown 6-DCH18C6

摘要

Process for separating the isomers of a crown ether, making it possible in particular to recover the pure cis-syn-cis isomer of DCH 18C6. …??This process comprises the following stages: … …  a) dissolving in an organic solvent a mixture of the isomers of the said crown ether comprising the cis-anti-cis isomer and the cis-syn-sis isomer, …  b) adding uranyl nitrate to the solution obtained in stage a) in such quantity that practically all the isomers of the crown ether except for the cis-syn-cis isomer are precipitated in the form of complexes with uranyl nitrate, …  c) separating off the precipitate thus formed, and …  d) recovering the pure cis-syn-cis isomer in the solution, and …  e) recovering the pure cis-anti-cis isomer from the precipitate. … …IMAGE…