首页> 外国专利> (Arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and use as anti-epileptic, neuroprotective and antidepressant agents, and their use as therapeutic agents for epilepsy, neuroprotective agents and antidepressants )

(Arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and use as anti-epileptic, neuroprotective and antidepressant agents, and their use as therapeutic agents for epilepsy, neuroprotective agents and antidepressants )

机译:(芳烷基氨基苄基)氨基丙酰胺衍生物,其制备和用作抗癫痫药,神经保护药和抗抑郁药以及用作癫痫的治疗药,神经保护药和抗抑郁药)

摘要

The present invention is active against the central nervous system (CNS), including epilepsy, Parkinson's disease, neuroprotective agents. (I) and (I A) and pharmaceutically acceptable salts thereof, which can be used in the treatment of depression, convulsions, and hypnotics.;Wherein n is an integer from 1 to 4; R and RlMay be the same or different and are hydrogen, halogen, trifluoromethyl or COne-C4Alkoxy, R2Is hydrogen or COne-C4Alkyl; At the same time, R is hydrogen and RlIs hydrogen or halogen and n is 1, R2Is not hydrogen or methyl; R3Is halogen.
机译:本发明对包括癫痫,帕金森氏病,神经保护剂在内的中枢神经系统(CNS)具有活性。 (I)和(I A)及其药学上可接受的盐,可用于治疗抑郁症,惊厥和催眠药。其中n为1至4的整数。 R和R l 可以相同或不同,并且可以是氢,卤素,三氟甲基或C One -C 4 烷氧基,R 2 是氢或C One -C 4 烷基;同时,R是氢,R 1 是氢或卤素,n是1,R 2 不是氢或甲基。 R 3 是卤素。

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