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Dynamical destabilization of systems characterized by kinetically coupled components using a differential flow

机译:系统的动态失稳,其特征在于使用差分流进行动力学耦合的组件

摘要

A method of destabilizing the homogeneous steady state of a dynamical system with two or more dynamically coupled variables through the action of a differential bulk flow of the key species, termed Differential Flow Induced Instability (DIFII), is disclosed. The DIFII is also applicable to systems with time periodic (limit cycle) and aperiodic (chaotic) states. Turing predicted that in systems characterized by activator/inhibitor kinetics a homogeneous, stable steady state of the reactive system may lose its stability and form inhomogeneous patterns due to the interaction of diffusion and reaction when the diffusion coefficient of the inhibitor is sufficiently greater than that of the activator. This mechanism is believed to form the basis of biological morphogenesis. The method of the present invention avoids this constraint on the diffusivities in the dynamically coupled two component system by using a differential bulk flow between the activator and the inhibitor species rather than a differential diffusivity. In systems with three (or more) dynamically coupled components the requirement of the presence of an activator species (or subsystem) is relaxed and if there is no activator species (or subsystem) present, the system may be destabilized by a differential flow of its components, in contrast to systems of two dynamical variables. Technological advantages such as reaction yield enhancement are shown. The method disclosed herein is shown to be applicable to a wide range of systems including chemical, biological and physical.
机译:公开了一种通过关键物质的微分总流量的作用来使具有两个或更多个动态耦合变量的动力学系统的均质稳态不稳定的方法,该方法称为微分流量引起的不稳定性(DIFII)。 DIFII也适用于具有时间周期性(极限周期)和非周期性(混沌)状态的系统。 Turing预测,在以活化剂/抑制剂动力学为特征的系统中,当抑制剂的扩散系数足够大时,由于扩散和反应的相互作用,反应体系的均匀,稳定的稳态可能会失去其稳定性并形成不均匀的模式。激活剂。据信该机制形成生物学形态发生的基础。本发明的方法通过使用活化剂和抑制剂物质之间的差异体积流量而不是差异扩散率,避免了对动态耦合两组分系统中扩散率的这种限制。在具有三个(或更多)动态耦合组件的系统中,对激活剂物质(或子系统)的存在的要求得到了缓解,如果不存在激活剂物质(或子系统),则系统可能会因其流动不同而不稳定。与两个动态变量的系统相反。显示了诸如提高反应产率的技术优势。示出了本文公开的方法可应用于包括化学,生物和物理的广泛系统。

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