Brazilian ginseng derivatives for treatment of sickle cell symptomatology

摘要

A process for extracting and isolating compounds from the Brazilian ginseng plant, particularly of the genus Pfaffia and most particularly Pfaffia paniculata, results in therapeutic compositions for treatment of sickle cell symptomatology. The extracted compositions are made by crushing the Brazilian ginseng roots, washing the crushed roots in hot alcohol, and then drying and grinding the roots into a powder. The powder is then treated using N-butanol and chromatography to extract the therapeutic compositions. Administration of a therapeutically-effective amount of the Brazilian ginseng compositions to subjects having sickle cell disease symptoms results in increased hemoglobin levels, inhibited red blood cell sickling and generally improved physical condition during the treatment.