NEW DERIVATIVES OF BICYCLIC AMINO ACIDS, METHODS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR APPLICATION, AND NEW BICYCLIC AMINO ACIDS AS INTERMEDIATE PRODUCTS, AND METHODS FOR THEIR PREPARATION

摘要

The bicyclic amino acid derivatives have the formula in which the hydrogen atoms on the bridges with atoms 3a and (6 + n) a are transconfigured with respect to each other, and the radicals have the meanings indicated. The compounds and their salts have a long antihypertensive effect. They are potent inhibitors of the angiotensin converting enzyme and can be used to treat hypertension of different origin.