PROCEDURE FOR OBTAINING CELLULAR LINES OF HYBRIDOMAS WHICH PRODUCE MONOCLONAL ANTI-BODIES WHICH IDENTIFY HEMATIES OF THE A AND AB BLOOD GROUPS AND THE APPLICATION OF THESE HEMOCLASSIFIED REACTIVE ANTI-BODIES

摘要

Relates to the biomedical sciences, especially with the immunology, the 15 hybridoma IHI obtained.Antibodies recognize specific epitopes which determine the specificity of Blood groups a and AB) in the erythrocyte membrane.Detect variants with weak expression of these Antigens, and did not bind to other structures.The Antibodies can be used as Reagents for the identification of phenotypic Cell Blood groups a and AB SCcording to the Abo System.The Hematology and hemotherapy,In particular, a process to obtain a hybridoma cell line secreting Monoclonal Antibodies (MoAbs) that includesAnd the Immunization of Balb / C MICE with human Erythrocytes Group aint,The fusion of Antibody producing cells with cells "Immortals" at room temperature and the selection and Cloning of hybridomas ProdUctores of these MAB, as well as !