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Method for vascular embolization and vascular embolizing agent

机译:血管栓塞方法及血管栓塞剂

摘要

A method for vascular embolization of a blood vessel of a patient comprises introducing a novel vascular embolizing agent which is an aqueous solution of a specific thermosensitive polymer, which is liquid at low temperatures but causes coagulation when heated to the body temperature of the patient, into the blood vessel followed by in situ heating of the solution. The thermosensitive polymer found to be suitable for the purpose is a homopolymer or copolymer of an N-substituted (meth)acrylamide monomer having a specified intrinsic viscosity in tetrahydrofuran and gives an aqueous solution capable of exhibiting phase transition from a liquid to a coagulate at a transition temperature of 10 to 37 °C.
机译:一种用于患者血管的血管栓塞的方法,包括将新型的血管栓塞剂引入到特定的热敏聚合物的水溶液中,该特定的热敏聚合物的水溶液在低温下为液体,但是当加热至患者的体温时引起凝结。血管,然后原位加热溶液。发现适合于该目的的热敏聚合物是在四氢呋喃中具有特定特性粘度的N-取代的(甲基)丙烯酰胺单体的均聚物或共聚物,并给出一种能够在室温下从液体到凝结物发生相变的水溶液。转变温度为10至37°C。

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