A transdermal therapeutic system for administering a pleiotropin through the skin, and a method for producing such a system (TRANSDERMAL THERAPEUTIC SYSTEM FOR ADMINISTRATION PHYSOSTIGMIN THROUGH THE SKIN AND A METHOD OF PRODUCING THE SYSTEM)

摘要

The present invention relates to an adhesive layer comprising an opaque backing layer which is impermeable to the active ingredient, from 40 to 90% by weight of a polymeric material and from 0.1 to 20% by weight of a sebostigmine substrate or a pharmaceutically acceptable salt thereof, And a removable protective layer covering the storage layer. The present invention relates to a percutaneous treatment system for administering pleiostigmine through the skin. The storage layer contains an acrylate and / or methacrylate polymer material and 0.1 to 40 wt% of a plasticizer containing a hydroxyl group and having an HLB value of 1.1 to 12.0.