METHOD OF PRIMARY LIVER CANCER TREATMENT AND KIT FOR PRIMARY LIVER CANCER TREATMENT

摘要

FIELD: medicine, oncology. SUBSTANCE: method involves administration of doxorubicin dissolved in lipiodol ultrafluid in hepatic artery. Doxorubicin preparation used - doxorubicin-estrone dissolved in 96% ethanol at 70-76 C, dose is 20-60 mg per 10-15 ml lipiodol ultrafluid. Preliminary, 20 min. before, alpha-fetoprotein is administrated in hepatic artery at dose 2-10 mg in 12-15 saline solution and repeated treatment is carried out in 3-4 weeks. Kit for treatment contains doxorubicin preparation and lipiodol ultrafluid, and doxorubicin preparation is sterile doxorubicin-estrone (20-60 mg in vials, volume is 15 ml), sterile lipiodol ultrafluid in two ampoules by 10 ml and, additionally, sterile lyophilized preparation of human alpha-fetoprotein at amount 1-10 mg in vials by 10 ml, sterile saline solution (15 ml in ampoule) and 96% ethanol (5 ml in ampoule). Method can be used for chemotherapy of oncological patients. EFFECT: improved method of treatment. 3 cl, 1 tbl