DETECTION OF HUMAN URINARY BLADDER CANCER CELL IN URINE SAMPLE BY MEASURING EXISTENCE OF TELOMERASE ACTIVITY

摘要

PROBLEM TO BE SOLVED: To noninvasively assay urinary bladder cancer in good sensitivity by measuring telomerase activity having positive relationship with existence of urinary bladder cancer cell. ;SOLUTION: The increase of a level of telomerase activity in released cell of urine sample of a patient to reference level is measured and the existence of urinary bladder cancer cell, especially urinary bladder cancer cell at low stage is sharply and specifically diagnosed. The cystoscopy of the cell is unnecessary even in a patient which exhibits incorrect negative cytologic result.;COPYRIGHT: (C)1997,JPO