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use of nerve growth factor in the preservation of corneas in culture, and the production of corneal and conjunctival tissues in vitro and in the treatment of corneal and conjunctival disorders
use of nerve growth factor in the preservation of corneas in culture, and the production of corneal and conjunctival tissues in vitro and in the treatment of corneal and conjunctival disorders
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机译:神经生长因子在体外保存角膜,体外生产角膜和结膜组织以及治疗角膜和结膜疾病中的应用
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摘要
The nerve growth factor (NGF) is used for the storage of corneas in culture, for the production and the storage in vitro of single cell populations of the corneal morphological and functional unit (i.e. epithelium, stroma/keratocytes and endothelium) and of the conjunctival epithelium, and for the production and the storage of corneal and conjunctival tissues, in particular for transplantation purposes. The NGF is also proposed for use in the therapy and/or the prophylaxis of diseases of the corneal surface, wherein a lack of integrity of the corneal and conjunctival morphological and functional unit occurs, in particular for pathologies having a dystrophic or neurodystrophic basis, both congenital and acquired.
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