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Controlled release of mydric and mydritic medicinal products in the anterior chamber

机译:在前房中控释散瞳和散瞳药物

摘要

The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.
机译:本发明涉及在眼科手术期间保持眼睛前房的结构完整性,从而保护形成并排成前节的组织免受潜在损害并同时持续提供miotic或散瞳剂的组合物。本发明提供了包含粘弹性聚合物的组合物,其中通过离子相互作用介导了miotic或散瞳剂的持续释放,以及提供了其中通过微囊或共聚物胶束介导的miotic或散瞳剂的持续释放的组合物。

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