CATHEPSIN K MOLECULE, A PEPTID BEING BONDED TO THE HOLLOW OF ACTIVE POSITON OF CATHEPSIN K, A COMPOSITION, METHOD FOR IDENTIFICATION OF INHIBITING COMPOUND AND INHIBITORS BEING COMPETITIVELY BONDED TO THE ACTIVE POSITION OF CATHEPSIN K

摘要

A novel cathepsin K crystalline stucture is identified. Also disclosed are methods of identifying inhibitors of this protease and methods of inhibiting cathepsin K using inhibitors with certain structural, physical and spatial characteristics.